Chamorro‐Garcia, A., Fetter, L., Emmons, N. A., Alfonsini, M., Paialunga, E., Glahn‐Martínez, B., Valenti, G., Porchetta, A., Kippin, T.E., Plaxco, K. W., Idili A.* (corr. author).
Electrochemical DNA‐Based Biosensors for In Vivo Quantification of a Therapeutic Protein. Small Structures
2026, 7(7), e70539. (OPEN ACCESS)
2025
Laboratory of Translational Chemistry
Chamorro-Garcia, A., Alfonsini, M., Caprioli, D., Parolo, C., & I Idili A.* (corr. author).
Continuous monitoring of biomolecular targets in vivo using DNA-based electrochemical sensors. Current Opinion in Electrochemistry
2025, 101765.
Laboratory of Translational Chemistry
Antonelli, G., Chamorro‐Garcia, A., Mencattini, A., Spitalieri, P., Sangiuolo, F., Filippi, J., ... & Idili A.* (co-corr. author), Martinelli, E.
Continuous pH Monitoring in Organ‐on‐Chip Devices with Single‐Step Fabricated DNA Scaffold Sensors Conjugated Hydrogels and Machine Learning. Advanced Functional Materials
2025, 35(36), 2501659. (OPEN ACCESS)
Featured in the back cover page of Advanced Functional Materials
Laboratory of Translational Chemistry
Ueno, K., Tsukakoshi, K., Takeuchi, N., Inaba, S., Idili, A., Porchetta, A., ... & Ikebukuro, K.
Bright and pH-sensitive Baby Spinach aptamer with RNA triplex fusion. Nucleic Acids Research
2025, 53(11), gkaf151. (OPEN ACCESS)
Laboratory of Translational Chemistry
Yang Q., Pedreira-Rincón J., Balerdi-Sarasola L., Baptista-Pires L., Muñoz J., Camprubí-Ferrer D. , Idili A., Parolo C.
An aptamer-based electrochemical sensor for the quantification of the malaria biomarker lactate dehydrogenase. Biosensors and Bioelectronics
2025, 274: 117152. . (OPEN ACCESS)
2024
Laboratory of Translational Chemistry
Gerson J., Erdal M. K., Dauphin‐Ducharme P., Idili A., Hespanha J. P., Plaxco K. W., Kippin T. E.
A high‐precision view of intercompartmental drug transport via simultaneous, seconds‐resolved, in situ measurements in the vein and brain. British Journal of Pharmacology
2024, 181(20): 3869-3885.
Laboratory of Translational Chemistry
Hu L., Rossetti M., Bergua J. F., Parolo C., Álvarez-Diduk R., Rivas L., Idili A.* (co-corr. author), Merkoçi A.
Harnessing Bioluminescent Bacteria to Develop an Enzymatic-free Enzyme-linked immunosorbent assay for the Detection of Clinically Relevant Biomarkers. ACS applied materials & interfaces
2024; 16(24):30636-30647. - Featured in the cover page of ACS applied materials & interfaces
Laboratory of Translational Chemistry
Bagheri N., Chamorro A., Idili A., Porchetta A.
PAM‐Engineered Toehold Switches as Input‐Responsive Activators of CRISPR‐Cas12a for Sensing Applications. Angewandte Chemie International Edition
2024; 63(17): e202319677.
2023
A. Merkoci Postdoc
Rivas L., Hu L., Parolo C., Idili A., Merkoçi, A.
Rational Approach to Tailor Au–IrO2 Nanoflowers as Colorimetric Labels for Lateral Flow Assays. ACS Applied Nano Materials
2023; 6(6): 4151-4161.
A. Merkoci Postdoc
Scroccarello A., Álvarez-Diduk R., Della Pelle F., de Carvalho Castro e Silva C., Idili A., Parolo C., Compagnone D., Merkoçi A.
One-Step Laser Nanostructuration of Reduced Graphene Oxide Films Embedding Metal Nanoparticles for Sensing Applications. ACS Sensors
2023; 8(2): 598–609.
Laboratory of Translational Chemistry
Mariottini, D., Idili, A.* (co-first and co-corr. author), Ercolani, G., Ricci F.
Thermo-programmed synthetic DNA-based receptors. ACS Nano
2023; 17(3): 1998–2006.
Laboratory of Translational Chemistry
Parolo C., Idili A., Heikenfeld J., Plaxco K.W.
Conformational-switch biosensors as novel tools to support continuous, real-time molecular monitoring in lab-on-a-chip devices. Lab on a Chip
2023; 23: 1339-1348.
2022
Laboratory of Translational Chemistry
Chamorro-Garcia A., Parolo C., Ortega G., Idili A., Green J., Ricci F., Plaxco K.W.
The sequestration mechanism as a generalizable approach to improve the sensitivity of biosensors and bioassays. Chem. Science
2022; 13(41): 12219-12228.
A. Merkoci Postdoc
Idili A., Bonini A., Parolo C., Alvarez-Diduk R., Di Francesco F., Merkoçi, A.
A programmable electrochemical Y-shaped DNA scaffold sensor for the single-step detection of antibodies and proteins in untreated biological fluids. Advanced Functional Materials
2022; 32(37): 2201881.
A. Merkoci Postdoc
Sena‐Torralba A., Torné‐Morató H., Parolo C., Ranjbar S., Farahmand Nejad M. A., Álvarez‐Diduk R., Idili A., Hormozi‐Nezha M., Merkoçi, A
A Novel Ratiometric Fluorescent Approach for the Modulation of the Dynamic Range of Lateral Flow Immunoassays. Advanced Materials Technologies
2022: 2101450.
A. Merkoci Postdoc
Hu L., Calucho E., Fuentes-Chust C., Parolo C., Idili A., Alvarez-Diduk R., Rivas, L., Merkoçi, A.
Selection and characterisation of bioreceptors to develop nanoparticle-based lateral-flow immunoassays in the context of the SARS-CoV-2 outbreak. Lab on a Chip
2022; 22(16): 2938–2943.
A. Merkoci Postdoc
Pereira C., Parolo C., Idili A., Gomis R., Rodrigues L., Sales G., Merkoçi A.
Paper-based biosensors for cancer diagnostics. Trends in Chemistry
2022; 4(6): 554–567.
A. Merkoci Postdoc
Bergua J.F., Álvarez-Diduk R., Idili A., Parolo C., Maymò M., Hu, L., Merkoçi, A.
Low-Cost, User-Friendly, All-Integrated Smartphone-Based Microplate Reader for Optical-Based Biological and Chemical Analyses. Analytical Chemistry
2022; 94(2): 1271–1285. - Among “most read articles” of the month of Analytical Chemistry (February-May 2022)
2021
A. Merkoci Postdoc
Rosati G., Idili A., Parolo C., Fuentes-Chust C., Calucho E., Hu L., de Carvalho Castro e Silva C., Rivas, L., Nguyen E., Bergua J.F., Alvarez-Diduk R., Munoz J., Junot C., Penon O., Monferrer D., Delamarche E., Merkoçi, A.
Nanodiagnostics to Face SARS-CoV-2 and Future Pandemics: From an Idea to the Market and beyond. ACS Nano
2021; 15(11): 17137–17149.
A. Merkoci Postdoc
Idili A., Parolo C., Alvarez-Diduk R., Merkoçi, A.
Rapid and Efficient Detection of the SARS-CoV-2 Spike Protein Using an Electrochemical Aptamer-Based Sensor. ACS sensors
2021; 6(8): 3093–3101. - Among “most read articles” of year (last 12 months) of ACS sensors (February-March 2022)
K. Plaxco Postdoc
Idili A., Gerson J., Kippin T., Plaxco K. W.
Seconds-resolved, in situ measurements of plasma phenylalanine disposition kinetics in living rats. Anal. Chem.
2021; 93(8): 4023-4032.
2020
F. Ricci Postdoc
Bertucci A., Porchetta A., Del Grosso E., Patino T., Idili A., Ricci F.
Protein‐controlled Actuation of Dynamic Nucleic Acid Networks Using Synthetic DNA Translators. Angew. Chem. Int. Ed.
2020; 59(46): 20577-20581.
K. Plaxco Postdoc
Parolo C., Idili A., Ortega G., Csordas A., Hsu A., Arroyo-Currás N., Yang Q., Ferguson B.S., Wang J., Plaxco K.W.
Real-Time Monitoring of a Protein Biomarker. ACS sensors
2020; 5(7): 1877-1881.
F. Ricci Postdoc
Engelen W., Zhu K., Subedi N., Idili A., Ricci F., Tel J., Merkx M.
Programmable Bivalent Peptide-DNA Locks for pH-Based Control of Antibody Activity. ACS Central Science
2020; 6(1): 22-31.
2019
K. Plaxco Postdoc
Idili A., Parolo C., Ortega G., Plaxco K.W.
Calibration-Free Measurement of Phenylalanine Levels in the Blood Using an Electrochemical Aptamer-Based Sensor Suitable for Point-of-Care Applications. ACS Sensors
2019; 4(12) : 3227-3233.Selected for the virtual issue on “Giants in Sensing” featuring some fifty articles from influential sensing researchers who have contributed to Anal. Chem., ACS Sensors and J. Am. Chem. Soc. in the past five years.
K. Plaxco Postdoc
Idili A., Gerson J., Parolo C., Kippin T., Plaxco K. W.
An electrochemical aptamer-based sensor for the rapid and convenient measurement of L-tryptophan. Anal. Bioanal. Chem.
2019; 411(19): 4629-4635.
K. Plaxco Postdoc
Rossetti M., Del Grosso E., Ranallo S., Mariottini D., Idili A., Bertucci A., Porchetta A.
Programmable RNA-based systems for sensing and diagnostic applications. Anal. Bioanal. Chem.
2019; 411(19): 4293-4302.
F. Ricci Postdoc
Mariottini D., Idili A., Nijenhuis M. A., Ercolani G., Ricci F.
Entropy-based rational modulation of the pKa of a synthetic pH-dependent nanoswitch. J. Am. Chem. Soc.
2019; 141(29): 11367-11371.
K. Plaxco Postdoc
Idili A., Arroyo-Currás N., Ploense K. L., Csordas A., Kuwahara M., Kippin T., Plaxco K. W.
Seconds-resolved pharmacokinetic measurements of the chemotherapeutic irinotecan in situ in the living body. Chem. Science
2019; 10(35): 8164-8170.
2018
F. Ricci Postdoc
Mariottini D., Idili A., Nijenhuis M. A., de Greef T., Ricci, F.
DNA-based nanodevices controlled by purely entropic linker domains. J. Am. Chem. Soc.
2018; 140(44): 14725–14734.
F. Ricci Postdoc
Ottaviani A., Iacovelli F., Idili A., Falconi M., Ricci F., Desideri A.
Engineering a responsive DNA triple helix into an octahedral DNA nanostructure for a reversible opening/closing switching mechanism: a computational and experimental integrated study. Nucleic Acids Res.
2018; 46(19=: 9951-9959.
2017
F. Ricci Postdoc
Hu D., Cecconello A., Idili A. (co-first author), Ricci F., Willner I.
Triplex DNA Nanostructures: From Basic Properties to Applications. Angew. Chem. Int. Ed.
2017, 56(48): 15210-15233.
F. Ricci Postdoc
Idili A., Ricci F., Vallée-Bélisle A.
Determining the folding and binding free energy of DNA-based nanodevices and nanoswitches using urea titration curves. Nucleic Acids Res.
2017; 45(13): 7571-7580.
F. Ricci Postdoc
Mariottini D., Idili A. (co-first author), Vallée-Bélisle A., Plaxco K. W., Ricci F.
A DNA nanodevice that loads and releases a cargo with hemoglobin-like allosteric control and cooperativity. Nano Lett.
2017; 17(5): 3225–3230.
F. Ricci Postdoc
Ranallo S., Prévost-Tremblay C., Idili A., Vallée-Bélisle A., Ricci F.
Antibody powered nucleic acid release using a DNA-based nanomachine. Nat. Commun.
2017; 8: 15150.-Featured in the following news media (C&EN, E&T Magazine, The Engineer, GEN, etc.)-Featured in the following Italian media (SkyTg24, Focus, ADNKronos, Galileo, etc.).-N°1 most read article of Nature Communications (May 2017).
F. Ricci Postdoc
Iacovelli F., Idili A. (co-first author), Benincasa A., Mariottini D., Ottaviani A., Falconi M.; Ricci F., Desideri A.
Simulative and experimental characterization of a pH-dependent clamp-like DNA triple helix nanoswitch. J. Am. Chem. Soc.
2017; 139(15): 5321–5329.
F. Ricci Postdoc
Kuzyk A., Urban M. J., Idili A. (co-first author), Ricci F., Liu N.
Selective control of reconfigurable chiral plasmonic metamolecules. ScienceAdvances
2017; 3(4): e1602803.-Featured in the several news media (AzoNano, ScienceDaily, PhysOrg, etc.).
F. Ricci Postdoc
Rossetti M., Ranallo S., Idili A., Porchetta A., Ricci F.
Allosteric DNA nanoswitches for controlled release of a molecular cargo triggered by biological inputs. Chem. Science
2017; 8(2): 914-920.-Featured in the cover page of Chemical Science
2016
F. Ricci Postdoc
Del Grosso E., Idili A., Porchetta A., Ricci F.
A modular clamp-like mechanism to regulate the activity of nucleic-acid target-responsive nanoswitches with external activators. Nanoscale
2016; 8(42): 18057-18061.-Featured in the cover page of Nanoscale
F. Ricci Postdoc
Ranallo S., Amodio A., Idili A., Porchetta A., Ricci F.
Electronic control of DNA-based nanoswitches and nanodevices. Chem. Science
2016; 7(1): 66-71.-Featured in the cover page of Chemical Science
2015
Master Degree
Idili A., Porchetta A., Amodio A., Vallée-Bélisle A., Ricci F.
Controlling Hybridization Chain Reactions with pH. Nano Lett.
2015; 15(8): 5539–5544.
Master Degree
Porchetta A., Idili A. (co-first author), Vallée-Bélisle A., Ricci F.
A general strategy to introduce pH-induced allostery in DNA-based receptors to achieve controlled release of ligands. Nano Lett.
2015; 15(7): 4467–4471.
2014
Master Degree
Amodio A.,Bin Z., Porchetta A., Idili A., Castronovo M., Fan C., Ricci F.
Rational Design of pH-Controlled DNA Strand Displacement. J. Am. Chem. Soc.
2014; 136(47): 16469–16472.
Master Degree
Idili A., Amodio A., Vidonis M., Feinberg-Somerson J., Castronovo M., Ricci F.
Folding-Upon-Binding and Signal-On Electrochemical DNA Sensor with High Affinity and Specificity. Anal. Chem.
2014; 86(18): 9013–9019.-Featured in the cover page of Analytical Chemistry-Among “most read articles” of Analytical Chemistry (August 2014)
Master Degree
Puiu M., Idili A., Moscone D., Ricci F., Bala C.
A modular electrochemical peptide-based sensor for antibody detection. Chem. Comm.
2014; 50(64): 8962-8965.
Master Degree
Idili A., Vallée-Bélisle A., Ricci F.
Programmable pH-triggered DNA nanoswitches. J. Am. Chem. Soc.
2014; 136(16): 5836–5839.-Featured in the following news media (sciencedaily, sciencenewsline, etc.).
Master Degree
Idili A., Plaxco K. W., Vallée-Bélisle A., Ricci F.
Thermodynamic Basis for Engineering High-Affinity, High-Specificity Binding-Induced DNA Clamp Nanoswitches. ACS Nano
2013; 7(12): 10863–10869.-Featured in several news media (sciencedaily, kuwaittimes, montreal azzette, etc.).
LIST OF BOOK CHAPTERS
Chamorro-Garcia A., Ortega-Quintanilla G., Idili A.* (co-corr. author), Parolo, C.
Structure switching bioreceptors as novel tools for point-of-care diagnostics.
Biotechnology advances in Disease Diagnosis
International Encyclopedia of Public Health, 3rd Edition 2024 (Elsevier).
Hu L., Idili A., Parolo C., Alvarez-Diduk R., Calucho E., Merkoçi, A.
Optical smartphone-based sensing: diagnostic of biomarkers.
The Detection of Biomarkers: Past, Present, and the Future Prospects
2022 (pp. 277-302). Academic Press.
Idili A., Monton, H., Meidna-Sanchez M., Ibarlucea B., Cuniberti G., Schmidt O., Plaxco K., Parolo C.
Continuous monitoring of molecular biomarkers in microfluidic devices.
Progress in Molecular Biology and Translational Science
2022 - Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications-Part B, 295.
Idili A., Ricci F.
Design and Characterization of pH-Triggered DNA Nanoswitches and Nanodevices Based on DNA Triplex Structures.
Methods Mol. Bio.